Heteroclitic proliferative responses and changes in cytokine profile induced by altered peptides: Implications for autoimmunity

Productive engagement of T cell receptors (TCRs) by cognate ligand (major histocompatibility complex plus peptide) leads to proliferation, differentiation, and the elaboration of effector functions. Altered peptides generated by single amino acid substitutions in the antigenic peptide have diverse e...

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Bibliographische Detailangaben
Hauptverfasser: Nicholson, Lindsay B., Waldner, Hanspeter, Carrizosa, Ana M., Sette, Alessandro, Collins, Mary, Kuchroo, Vijay K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1998
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18196/
https://ncbi.nlm.nih.gov/pubmed/9419364
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