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ABILITY OF HERPES SIMPLEX VIRUS VECTORS TO BOOST IMMUNE RESPONSES TO DNA VECTORS AND TO PROTECT AGAINST CHALLENGE BY SIMIAN IMMUNODEFICIENCY VIRUS

The immunogenicity and protective capacity of replication-defective herpes simplex virus (HSV) vector-based vaccines were examined in rhesus macaques. Three macaques were inoculated with recombinant HSV vectors expressing Gag, Env, and a Tat-Rev-Nef fusion protein of simian immunodeficiency virus (S...

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Bibliographic Details
Main Authors: Kaur, Amitinder, Sanford, Hannah B., Garry, Deirdre, Lang, Sabine, Klumpp, Sherry A., Watanabe, Daisuke, Bronson, Roderick T., Lifson, Jeffrey D., Rosati, Margherita, Pavlakis, George N., Felber, Barbara K., Knipe, David M., Desrosiers, Ronald C.
Format: Artigo
Language:Inglês
Published: 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1819472/
https://ncbi.nlm.nih.gov/pubmed/16962628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.08.007
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