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The pre-M1 segment of the α1 subunit is a transduction element in the activation of the GABA(A) receptor
The binding of the neurotransmitter GABA induces conformational changes in the GABA(A) receptor (GABA(A)R), leading to the opening of a gate that controls ion permeation through an integral transmembrane pore. A number of structural elements within each subunit, located near the membrane interface,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1819431/ https://ncbi.nlm.nih.gov/pubmed/16763005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.102756 |
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