The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light

In Saccharomyces cerevisiae, most mutations induced by a wide range of mutagens arise during translesion replication employing the REV1 gene product and DNA polymerase ζ. As part of an effort to investigate mammalian mutagenic mechanisms, we have identified cDNA clones of the human homologs of the y...

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Huvudupphovsmän: Gibbs, Peter E. M., Wang, Xi-De, Li, Ziqiang, McManus, Terrence P., McGregor, W. Glenn, Lawrence, Christopher W., Maher, Veronica M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2000
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC18191/
https://ncbi.nlm.nih.gov/pubmed/10760286
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