Pharmacokinetics and tolerance of acyclovir, a new anti-herpesvirus agent, in humans.

The pharmacokinetics and tolerance of acyclovir administered intravenously in single doses of 2.5, 5.0, 10.0, and 15.0 mg/kg were studied in 13 volunteers. The mean concentrations (+/- standard deviations) at the end of infusion as measured by radioimmunoassay were 4.52 +/0 0.31, 8.28 +/- 2.61, 14.6...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Laskin, O L, Longstreth, J A, Saral, R, de Miranda, P, Keeney, R, Lietman, P S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181902/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7103443/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.3.393
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