Pharmacokinetics and tolerance of acyclovir, a new anti-herpesvirus agent, in humans.

The pharmacokinetics and tolerance of acyclovir administered intravenously in single doses of 2.5, 5.0, 10.0, and 15.0 mg/kg were studied in 13 volunteers. The mean concentrations (+/- standard deviations) at the end of infusion as measured by radioimmunoassay were 4.52 +/0 0.31, 8.28 +/- 2.61, 14.6...

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Bibliographic Details
Main Authors: Laskin, O L, Longstreth, J A, Saral, R, de Miranda, P, Keeney, R, Lietman, P S
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC181902/
https://ncbi.nlm.nih.gov/pubmed/7103443
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