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An Investigation into the Mechanisms of DNA Strand Breakage by Direct Ionization of Variably Hydrated Plasmid DNA

The mechanisms by which ionizing radiation directly causes strand breaks in DNA were investigated by comparing the chemical yield of DNA-trapped free radicals to the chemical yield of DNA single strand break (ssb) and double strand break (dsb), as a function of hydration (Γ). Solid-state films of pl...

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Dettagli Bibliografici
Autori principali: Purkayastha, Shubhadeep, Milligan, Jamie R., Bernhard, William A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817901/
https://ncbi.nlm.nih.gov/pubmed/17181287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp065489i
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