Osteopenia in X-linked hyper-IgM syndrome reveals a regulatory role for CD40 ligand in osteoclastogenesis

We report that osteopenia is a prominent and previously unappreciated clinical feature of patients with X-linked hyper-IgM syndrome, an inherited immune deficiency disorder caused by mutations in the gene encoding CD40 ligand (CD40L). We therefore conducted studies to determine the relationship betw...

Full description

Saved in:
Bibliographic Details
Main Authors: Lopez-Granados, Eduardo, Temmerman, Stephane T., Wu, Lynne, Reynolds, James C., Follmann, Dean, Liu, Shuying, Nelson, David L., Rauch, Frank, Jain, Ashish
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817828/
https://ncbi.nlm.nih.gov/pubmed/17360404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605715104
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items