Functional consequence of mutation in rat cardiac troponin T is affected differently by myosin heavy chain isoforms

Cardiac troponin T (cTnT) is an essential component of the thin filament regulatory unit (RU) that regulates Ca(2+) activation of tension in the heart muscle. Because there is coupling between the RU and myosin crossbridges, the functional outcome of cardiomyopathy-related mutations in cTnT may be m...

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Hlavní autoři: Tschirgi, Matthew L, Rajapakse, Indika, Chandra, Murali
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2006
Témata:
Cardiovascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817786/
https://ncbi.nlm.nih.gov/pubmed/16644804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.107417
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