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Functional consequence of mutation in rat cardiac troponin T is affected differently by myosin heavy chain isoforms
Cardiac troponin T (cTnT) is an essential component of the thin filament regulatory unit (RU) that regulates Ca(2+) activation of tension in the heart muscle. Because there is coupling between the RU and myosin crossbridges, the functional outcome of cardiomyopathy-related mutations in cTnT may be m...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1817786/ https://ncbi.nlm.nih.gov/pubmed/16644804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.107417 |
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