Competition of beta-lactam antibiotics for the penicillin-binding proteins of Neisseria gonorrhoeae.

The affinities of nine structurally different beta-lactam antibiotics for the three major gonococcal penicillin-binding proteins (PBPs) were determined by using a competition assay with tritium-labeled penicillin and live, growing bacteria. Each determination was carried out in parallel in isogenic...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Dougherty, T J, Koller, A E, Tomasz, A
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1981
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181641/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6792979/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.20.1.109
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