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Competition of beta-lactam antibiotics for the penicillin-binding proteins of Neisseria gonorrhoeae.

The affinities of nine structurally different beta-lactam antibiotics for the three major gonococcal penicillin-binding proteins (PBPs) were determined by using a competition assay with tritium-labeled penicillin and live, growing bacteria. Each determination was carried out in parallel in isogenic...

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Detalhes bibliográficos
Main Authors: Dougherty, T J, Koller, A E, Tomasz, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC181641/
https://ncbi.nlm.nih.gov/pubmed/6792979
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