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Schizosacchromyces pombe Dpb2 Binds to Origin DNA Early in S Phase and Is Required for Chromosomal DNA Replication

Genetic evidence suggests that DNA polymerase epsilon (Pol ε) has a noncatalytic essential role during the early stages of DNA replication initiation. Herein, we report the cloning and characterization of the second largest subunit of Pol ε in fission yeast, called Dpb2. We demonstrate that Dpb2 is...

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Bibliografiske detaljer
Main Authors: Feng, Wenyi, Rodriguez-Menocal, Luis, Tolun, Gökhan, D'Urso, Gennaro
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC181578/
https://ncbi.nlm.nih.gov/pubmed/12925774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-02-0088
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