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Topoisomerase III is required for accurate DNA replication and chromosome segregation in Schizosaccharomyces pombe

The deletion of the top3(+) gene leads to defective nuclear division and lethality in Schizosaccharo myces pombe. This lethality is suppressed by concomitant loss of rqh1(+), the RecQ helicase. Despite extensive investigation, topoisomerase III function and its relationship with RecQ helicase remain...

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Autores principales: Oh, Misook, Choi, In-Soon, Park, Sang Dai
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC137115/
https://ncbi.nlm.nih.gov/pubmed/12235386
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