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Distinct Mechanisms of Agonist-induced Endocytosis for Human Chemokine Receptors CCR5 and CXCR4

Desensitization of the chemokine receptors, a large class of G protein–coupled receptors, is mediated in part by agonist-driven receptor endocytosis. However, the exact pathways have not been fully defined. Here we demonstrate that the rate of ligand-induced endocytosis of CCR5 in leukocytes and exp...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Venkatesan, Sundararajan, Rose, Jeremy J., Lodge, Robert, Murphy, Philip M., Foley, John F.
Format: Artigo
Langue:Inglês
Publié: American Society for Cell Biology 2003
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181569/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12925765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-11-0714
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