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Distinct Mechanisms of Agonist-induced Endocytosis for Human Chemokine Receptors CCR5 and CXCR4

Desensitization of the chemokine receptors, a large class of G protein–coupled receptors, is mediated in part by agonist-driven receptor endocytosis. However, the exact pathways have not been fully defined. Here we demonstrate that the rate of ligand-induced endocytosis of CCR5 in leukocytes and exp...

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Main Authors: Venkatesan, Sundararajan, Rose, Jeremy J., Lodge, Robert, Murphy, Philip M., Foley, John F.
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC181569/
https://ncbi.nlm.nih.gov/pubmed/12925765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-11-0714
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