Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisome
The synthesis of double-stranded DNA by a rolling circle mechanism was reconstituted in vitro with a replisome consisting of the DNA polymerase-UL42 complex and the heterotrimeric helicase-primase encoded by herpes simplex virus type 1. Okazaki fragments 3 kilobases in length and leading strands tha...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10760262/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.8.3896 |
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