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Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisome

The synthesis of double-stranded DNA by a rolling circle mechanism was reconstituted in vitro with a replisome consisting of the DNA polymerase-UL42 complex and the heterotrimeric helicase-primase encoded by herpes simplex virus type 1. Okazaki fragments 3 kilobases in length and leading strands tha...

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Autores principales: Falkenberg, Maria, Lehman, I. R., Elias, Per
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC18113/
https://ncbi.nlm.nih.gov/pubmed/10760262
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