Targeted inhibition of transcription elongation in cells mediated by triplex-forming oligonucleotides
Triple-helix-forming oligonucleotides (TFOs) bind in the major groove of double-stranded DNA at oligopyrimidine⋅oligopurine sequences and therefore are candidate molecules for artificial gene regulation, in vitro and in vivo. We recently have described oligonucleotide analogues containing N3′-P5′ ph...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2000
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10760257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.8.3862 |
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