A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo

The tumor suppressor p53 is a potent inducer of tumor cell death, and strategies exist to exploit p53 for therapeutic gain. However, because about half of human cancers contain mutant p53, application of these strategies is restricted. p53 family members, in particular p73, are in many ways function...

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Bibliografski detalji
Glavni autori: Bell, Helen S., Dufes, Christine, O’Prey, Jim, Crighton, Diane, Bergamaschi, Daniele, Lu, Xin, Schätzlein, Andreas G., Vousden, Karen H., Ryan, Kevin M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2007
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810568/
https://ncbi.nlm.nih.gov/pubmed/17347683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28920
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