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A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo
The tumor suppressor p53 is a potent inducer of tumor cell death, and strategies exist to exploit p53 for therapeutic gain. However, because about half of human cancers contain mutant p53, application of these strategies is restricted. p53 family members, in particular p73, are in many ways function...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Clinical Investigation
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1810568/ https://ncbi.nlm.nih.gov/pubmed/17347683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28920 |
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