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GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria

p73, a member of the p53 family, shares high sequence homology with p53 and shows many p53-like properties: it binds to p53-DNA target sites, transactivates p53-responsive genes and induces cell cycle arrest and apoptosis. Apart from this transcription-dependent effect, less is known about the downs...

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Autori principali: John, K, Alla, V, Meier, C, Pützer, B M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131914/
https://ncbi.nlm.nih.gov/pubmed/21127500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.153
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