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Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells
BACKGROUND: Many lines of evidence suggest that poly(ADP-ribose) polymerase-1 (Parp-1) is involved in transcriptional regulation of various genes as a coactivator or a corepressor by modulating chromatin structure. However, the impact of Parp-1-deficiency on the regulation of genome-wide gene expres...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1810537/ https://ncbi.nlm.nih.gov/pubmed/17286852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-41 |
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