ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells

Embryonic stem (ES) cells are in a dynamic equilibrium of distinct functional states, characterized by the heterogeneous expression of critical pluripotency factors and regulated by a spectrum of reversible histone modifications. Maintenance of this equilibrium is a hallmark of pluripotency. Here we...

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Detalhes bibliográficos
Main Authors: Roper, Stephen J., Chrysanthou, Stephanie, Senner, Claire E., Sienerth, Arnold, Gnan, Stefano, Murray, Alexander, Masutani, Mitsuko, Latos, Paulina, Hemberger, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132717/
https://ncbi.nlm.nih.gov/pubmed/25034692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku591
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