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Discrete Functional Elements Required for Initiation Activity of the Chinese Hamster Dihydrofolate Reductase Origin Beta at Ectopic Chromosomal Sites

The Chinese hamster dihydrofolate reductase (DHFR) DNA replication initiation region, the 5.8 kb ori-beta, can function as a DNA replicator at random ectopic chromosomal sites in hamster cells. We report a detailed genetic analysis of the DiNucleotide Repeat (DNR) element, one of several sequence el...

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Autors principals: Gray, Steven J., Liu, Guoqi, Altman, Amy L., Small, Lawrence E., Fanning, Ellen
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810229/
https://ncbi.nlm.nih.gov/pubmed/17078947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2006.09.020
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