Defined Sequence Modules and an Architectural Element Cooperate To Promote Initiation at an Ectopic Mammalian Chromosomal Replication Origin

A small DNA fragment containing the high-frequency initiation region (IR) ori-β from the hamster dihydrofolate reductase locus functions as an independent replicator in ectopic locations in both hamster and human cells. Conversely, a fragment of the human lamin B2 locus containing the previously map...

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Bibliographic Details
Main Authors: Altman, Amy L., Fanning, Ellen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC400449/
https://ncbi.nlm.nih.gov/pubmed/15121836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.10.4138-4150.2004
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