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Autoantibodies directed against the protease inhibitor calpastatin in psoriasis

Psoriasis is believed to be a T cell-mediated autoimmune disease, but also exhibits autoantibody production. Calpastatin is an endogenous inhibitor of calpain, a ubiquitous protease that regulates inflammatory processes. Anti-calpastatin autoantibody was first identified as an autoantibody specific...

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Detalles Bibliográficos
Main Authors: Matsushita, Y, Shimada, Y, Kawara, S, Takehara, K, Sato, S
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809283/
https://ncbi.nlm.nih.gov/pubmed/15654835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02701.x
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