Differential regulation of mast cell cytokines by both dexamethasone and the p38 mitogen-activated protein kinase (MAPK) inhibitor SB203580

Activated mast cells generate multiple cytokines but it is not known if these can be differentially regulated by pharmacological agents. We report here that the glucocorticoid dexamethasone (DEX) preferentially inhibited Ag-induced expression of IL-4 and IL-6 mRNA relative to TNF-α mRNA in RBL-2H3 c...

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Autores principales: KORANTENG, R D, SWINDLE, E J, DAVIS, B J, DEARMAN, R J, KIMBER, I, FLANAGAN, B F, COLEMAN, J W
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2004
Materias:
Basic Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809098/
https://ncbi.nlm.nih.gov/pubmed/15196247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02510.x
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