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Evaluation of conformational epitopes on thyroid peroxidase by antipeptide antibody binding and mutagenesis

Autoantibodies to thyroid peroxidase (TPO) recognize predominantly conformational epitopes, which are restricted to two distinct determinants, termed immunodominant domain region (IDR) A and B. These dominant determinants reside in the region with structural homology to myeloperoxidase (MPO)-like do...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: GORA, M, GARDAS, A, WIKTOROWICZ, W, HOBBY, P, WATSON, P F, WEETMAN, A P, SUTTON, B J, BANGA, J P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809007/
https://ncbi.nlm.nih.gov/pubmed/15030525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02422.x
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