Blocking B7 and CD40 co-stimulatory molecules decreases antiviral T cell activity

Inhibition of co-stimulatory signals for T cells by interrupting CD80/CD86–CD28 and CD40–CD154 interactions is a promising approach to prevent transplant rejection and to induce graft tolerance. However, this tolerizing treatment might affect T cell reactivity towards all the antigens to which the i...

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Hlavní autoři: VERMEIREN, J, CEUPPENS, J L, HAEGEL-KRONENBERGER, H, DE BOER, M, BOON, L, VAN GOOL, S W
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2004
Témata:
Basic Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808941/
https://ncbi.nlm.nih.gov/pubmed/14738453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2003.02363.x
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