N-acetylcysteine inhibits the induction of an antigen-specific antibody response down-regulating CD40 and CD27 co-stimulatory molecules

We investigated the effect of N-acetylcysteine (NAC) on normal human B cell functions. We found that NAC significantly inhibited both the induction of the specific antibody response to the T-dependent antigen Candida albicans and T-dependent pokeweed mitogen (PWM)-induced polyclonal Ig production. N...

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Bibliografiske detaljer
Main Authors: GIORDANI, L, QUARANTA, M G, MALORNI, W, BOCCANERA, M, GIACOMINI, E, VIORA, M
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2002
Fag:
Basic Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906440/
https://ncbi.nlm.nih.gov/pubmed/12165081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01897.x
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