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Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient
We used a GAD65-specific human B–T cell line cognate system in vitro to investigate the modulation of GAD65 presentation by autoantibody, assessed in a proliferation assay. Generally, if the T cell determinant overlaps or resides within the antibody epitope, effects of presentation are blunted while...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1808922/ https://ncbi.nlm.nih.gov/pubmed/14678267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02343.x |
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