T cell response pattern to glutamic acid decarboxylase 65 (GAD65) peptides of newly diagnosed type 1 diabetic patients sharing susceptible HLA haplotypes

Autoantibodies and autoreactive T lymphocytes directed against several pancreatic β cell proteins such as GAD65 have been identified in the circulation before and at the onset of clinical type 1 (insulin-dependent) diabetes. Using GAD65 synthetic peptides, we studied the proliferative response of pe...

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Detalhes bibliográficos
Main Authors: RHARBAOUI, F, MAYER, A, GRANIER, C, BOUANANI, M, THIVOLET, C, PAU, B, ORGIAZZI, J, MADEC, A -M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905465/
https://ncbi.nlm.nih.gov/pubmed/10403912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00945.x
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