Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient

We used a GAD65-specific human B–T cell line cognate system in vitro to investigate the modulation of GAD65 presentation by autoantibody, assessed in a proliferation assay. Generally, if the T cell determinant overlaps or resides within the antibody epitope, effects of presentation are blunted while...

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Bibliographic Details
Main Authors:	BANGA, J P, MOORE, J K, DUHINDAN, N, MADEC, A M, VAN ENDERT, P M, ORGIAZZI, J, ENDL, J
Format:	Artigo
Language:	Inglês
Published:	Blackwell Science Inc 2004
Subjects:	Basic Immunology
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1808922/ https://ncbi.nlm.nih.gov/pubmed/14678267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02343.x
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Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient

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