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Validation of the interleukin-10 knockout mouse model of colitis: antitumour necrosis factor-antibodies suppress the progression of colitis

Advances in understanding pathogenesis and developing new therapies are hastened by the use of effective animal models of disease. In inflammatory bowel disease, such as Crohn's disease, a variety of models have been used, including the IL-10 knockout mouse. However, in order to be truly valuab...

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Detalhes bibliográficos
Main Authors: SCHEININ, T, BUTLER, D M, SALWAY, F, SCALLON, B, FELDMANN, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808754/
https://ncbi.nlm.nih.gov/pubmed/12823276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02193.x
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