Leukocyte-Suppressing Influences of Interleukin (IL)-10 in Cardiac Allografts : Insights from IL-10 Knockout Mice

To investigate the role of interleukin (IL)-10 in late graft outcomes, we compared BALB/c donor hearts transplanted into immunosuppressed wild-type or IL-10 gene-deficient (−/−) C57BL recipients (n = 49) at 50 ± 5 days. There was prominent leukocyte infiltration and parenchymal destruction with more...

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Main Authors: Räisänen-Sokolowski, Anne, Glysing-Jensen, Troels, Russell, Mary E.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853400/
https://ncbi.nlm.nih.gov/pubmed/9811341
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