Local delivery of adenoviral vectors encoding murine interleukin 10 induces colonic interleukin 10 production and is therapeutic for murine colitis

Introduction: Interleukin 10 knockout (IL-10−/−) mice spontaneously develop a Th1 T cell mediated colitis with many similarities to Crohn’s disease. Daily injections of IL-10 are unable to induce remission in mice with established disease. In contrast, we have shown previously that intravenous admin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lindsay, J O, Ciesielski, C J, Scheinin, T, Brennan, F M, Hodgson, H J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Copyright 2003 by Gut 2003
Pynciau:
Inflammatory Bowel Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773714/
https://ncbi.nlm.nih.gov/pubmed/12801955
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg