Modulation of autoreactive responses of peripheral blood lymphocytes of patients with systemic lupus erythematosus by peptides based on human and murine anti-DNA autoantibodies

Two peptides, based on the sequences of the complementarity-determining regions (CDR) 1 and 3 of a pathogenic murine monoclonal anti-DNA autoatibody that bears the 16/6 idiotype (Id), were shown to either prevent or treat an already established systemic lupus erythematosus (SLE) in two murine models...

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Bibliographic Details
Main Authors: STHOEGER, Z M, DAYAN, M, TCHERNIACK, A, GREEN, L, TOLEDO, S, SEGAL, R, ELKAYAM, O, MOZES, E
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Inc 2003
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808619/
https://ncbi.nlm.nih.gov/pubmed/12562403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02058.x
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