Full Length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons

BACKGROUND: Bcl-2 homology domain (BH) 3-only proteins are pro-apoptotic proteins of the Bcl-2 family that couple stress signals to the mitochondrial cell death pathways. The BH3-only protein Bid can be activated in response to death receptor activation via caspase 8-mediated cleavage into a truncat...

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Hlavní autoři: König, Hans-Georg, Rehm, Markus, Gudorf, Daniel, Krajewski, Stan, Gross, Atan, Ward, Manus W, Prehn, Jochen HM
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808451/
https://ncbi.nlm.nih.gov/pubmed/17326836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-8-7
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