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Free energy of DNA duplex formation on short oligonucleotide microarrays

DNA/DNA duplex formation is the basic mechanism that is used in genome tiling arrays and SNP arrays manufactured by Affymetrix. However, detailed knowledge of the physical process is still lacking. In this study, we show a free energy analysis of DNA/DNA duplex formation these arrays based on the po...

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Bibliographic Details
Main Authors: Zhang, Li, Wu, Chunlei, Carta, Roberto, Zhao, Haitao
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1807971/
https://ncbi.nlm.nih.gov/pubmed/17169993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1064
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