The Delta intracellular domain mediates TGF-β/Activin signaling through binding to Smads and has an important bi-directional function in the Notch–Delta signaling pathway

Delta is a major transmembrane ligand for Notch receptor that mediates numerous cell fate decisions. The Notch signaling pathway has long been thought to be mono-directional, because ligands for Notch were generally believed to be unable to transmit signals into the cells expressing them. However, w...

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Библиографические подробности
Главные авторы: Hiratochi, Masahiro, Nagase, Hisashi, Kuramochi, Yu, Koh, Chang-Sung, Ohkawara, Takeshi, Nakayama, Kohzo
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2007
Предметы:
Molecular Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1807952/
https://ncbi.nlm.nih.gov/pubmed/17251195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1128
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