An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo

Activation of the endothelin receptor B (ETRB) in cultured melanocyte precursors promotes cell proliferation while inhibiting differentiation, two hallmarks of malignant transformation. We therefore tested whether ETRB has a similar role in malignant transformation of melanoma. When tested in cultur...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lahav, Ronit, Heffner, Garrett, Patterson, Paul H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500205/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11496
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!