An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo
Activation of the endothelin receptor B (ETRB) in cultured melanocyte precursors promotes cell proliferation while inhibiting differentiation, two hallmarks of malignant transformation. We therefore tested whether ETRB has a similar role in malignant transformation of melanoma. When tested in cultur...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500205/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11496 |
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