An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo

Activation of the endothelin receptor B (ETRB) in cultured melanocyte precursors promotes cell proliferation while inhibiting differentiation, two hallmarks of malignant transformation. We therefore tested whether ETRB has a similar role in malignant transformation of melanoma. When tested in cultur...

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Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Lahav, Ronit, Heffner, Garrett, Patterson, Paul H.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 1999
Gaiak:	Biological Sciences
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500205/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11496
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