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Selection of a Novel gp41-specific HIV-1 Neutralizing Human Antibody by Competitive Antigen Panning

The HIV envelope glycoprotein (Env) is composed of two non-covalently associated subunits: gp120 and gp41. Panning of phage-displayed antibody libraries against Env-based antigens has resulted mostly in selection of anti-gp120 antibodies. Native gp41 in the absence of gp120 is unstable. The use of g...

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Hlavní autoři: Zhang, Mei-Yun, Choudhry, Vidita, Sidorov, Igor A., Tenev, Vladimir, Vu, Bang K., Choudhary, Anil, Lu, Hong, Stiegler, Gabriela M., Katinger, Hermann W.D., Jiang, Shibo, Broder, Christopher C., Dimitrov, Dimiter S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805821/
https://ncbi.nlm.nih.gov/pubmed/17078964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2006.09.016
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