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Selection of a Novel gp41-specific HIV-1 Neutralizing Human Antibody by Competitive Antigen Panning
The HIV envelope glycoprotein (Env) is composed of two non-covalently associated subunits: gp120 and gp41. Panning of phage-displayed antibody libraries against Env-based antigens has resulted mostly in selection of anti-gp120 antibodies. Native gp41 in the absence of gp120 is unstable. The use of g...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1805821/ https://ncbi.nlm.nih.gov/pubmed/17078964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2006.09.016 |
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