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Cross-Reactive HIV-1 Neutralizing Monoclonal Antibodies Selected by Screening of an Immune Human Phage Library against an Envelope Glycoprotein (gp140) Isolated from a Patient (R2) with Broadly HIV-1 Neutralizing Antibodies

Elicitation of broadly cross-reactive neutralizing antibodies (bcnAbs) in HIV infections is rare. To test the hypothesis that such antibodies could be elicited by HIV envelope glycoproteins (Envs) with unusual immunogenic properties and to identify novel bcnAbs, we used a soluble Env ectodomain (gp1...

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Detalhes bibliográficos
Main Authors: Choudhry, Vidita, Zhang, Mei-Yun, Sidorov, Igor A., Louise, John M., Harris, Ilia, Dimitrov, Antony S., Bouma, Peter, Cham, Fatim, Choudhary, Anil, Rybak, Susanna M., Fouts, Timothy, Montefiori, David C., Broder, Christopher C., Quinnan, Gerald V., Dimitrov, Dimiter S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696119/
https://ncbi.nlm.nih.gov/pubmed/17306322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.01.015
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