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Renal cortical kinetics of gentamicin after implantation of gentamicin-polymethylmethacrylate beads in rats.

Beads of gentamicin-polymethylmethacrylate (Septopal), each containing 4.5 mg of gentamicin base, were implanted intraperitoneally in rats. Each rat received one bead. Serum levels and urinary excretion of gentamicin were maximal in the first day of treatment (0.6 micrograms/ml in serum 3 h after im...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Giuliano, R A, Verpooten, G A, De Broe, M E
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1986
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180565/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3777904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.3.385
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