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Correlation between renal membrane binding and nephrotoxicity of aminoglycosides.

The kinetics of aminoglycoside binding to renal brush border and basolateral membrane vesicles from rat renal cortex were studied by using [3H]amikacin. [3H]amikacin binding to renal membranes was found to be a rapid, saturable process with a fourfold greater affinity for basolateral membranes than...

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Bibliografiska uppgifter
Huvudupphovsmän: Williams, P D, Bennett, D B, Gleason, C R, Hottendorf, G H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1987
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC174778/
https://ncbi.nlm.nih.gov/pubmed/3606061
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