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Renal cortical kinetics of gentamicin after implantation of gentamicin-polymethylmethacrylate beads in rats.

Beads of gentamicin-polymethylmethacrylate (Septopal), each containing 4.5 mg of gentamicin base, were implanted intraperitoneally in rats. Each rat received one bead. Serum levels and urinary excretion of gentamicin were maximal in the first day of treatment (0.6 micrograms/ml in serum 3 h after im...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Giuliano, R A, Verpooten, G A, De Broe, M E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180565/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3777904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.3.385
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